ra-iwinyro.blogspot.com
area’s commercial real estats market saw a net absorption ofnegative 726,100 squares feet in the second quarter, the third straighrt quarter of negative absorption, according to . The commercial real estatee services firm says theWashington region’s office vacanc y rate has now reached 12.3 percent. Leases losses in the last three quartersmeant “virtually negatin g any growth in net demand we had in 2008,” said Kevi Thorpe, director of market research for Cassidy & Pinkards Colliers.
“There are flickering signs that the locap economy may be reaching an inflectionh point where conditions should beginhto improve, but the commercial industry still has a ways to go beforew demand returns in a meaningful way.” In D.C., net absorption was negative 230,900 square feet, pushing D.C.’se vacancy rate to 9.6 percent. In Northerjn Virginia, net absorption was negative 666,700 square Northern Virginia’s second quarter office vacancy rate climbeddto 13.6 percent.
Suburban Maryland’s office vacancy rate was 14 percent, with a positivr net absorption rateof 171,500o square feet in the second Thorpe predicts the growth in federalp government will lead to an increass in demand for office space, but says the Washingtoh area has more new space deliverinyg over the next two years than any other market in the As a result, “we are entering into a period of steadh rent declines,” he said.
Saturday, September 29, 2012
Friday, September 28, 2012
Thursday, September 27, 2012
Ullens Spotlights Chinese Architecture, Inspired by Duchamp - Wall Street Journal (blog)
ejoxot.wordpress.com
Wall Street Journal (blog) | Ullens Spotlights Chinese Architecture, Inspired by Duchamp Wall Street Journal (blog) But what the Ullens Center for Contemporary Art plans to show in its first architecture exhibition includes the drawing, film and other media by Yung Ho Chang, a Chinese architect who teaches at the Massachusetts Institute of Technology, cites ... |
Tuesday, September 25, 2012
5 Who Thrive: Four key changes enabled SuperGeeks to prosper - Minneapolis / St. Paul Business Journal:
deeshu-tatum.blogspot.com
Hawaii-based SuperGeeks opened three new computer serviced and repair centerslast month, one each on Maui, Oahu and the Big bringing the total to seven locationse statewide. He expects revenued to exceed $1.8 million this year, up almos t 40 percent from twoyears ago. who founded the business in credits most of the success to four changes he made in running the compant asits CEO: • Hiring a chief operatinhg officer. • Hiring business consultants. • Improving hiring standards. • Tapping into customer feedback.
Last August, Kerr hiredx Elena Ledoux to handle day-to-day operationw as chief operating “I see good companies as having threwelegs — the evangelizer, or myself; workersx to do the work; and management to handle daily Kerr said. “We were sort of limping alon gon two.” Ledoux, a lawyer who is based at the main servicse center at 2304 S. King St., overseess SuperGeeks’ staff of 25 and is implementing ways to measursedaily performance. That enables her to rewar d employees when goals are met and address issues when theyare not. “We’vs learned how to keep score,” Kerr said.
“Wer measure everything from performanceper technician, warrantt rates per technician, turnaround time, customert service. We measure it, post it and make the team aware of it.” SuperGeeks services computer systems at homes and offices as well as at its centers. Hourlu rates range between $60 and Half its business comes from directy consumers and half is from corporate customers who outsource theier information technology supportto SuperGeeks. Around the same time that he hirecd Ledoux, Kerr said he sought outside business help from twolocal consultants.
“I’m not a big fan of but sometimes your visiojn is restrictedwhen you’ve been in the busines for so long,” he said. SuperGeeks has been workingy with Ron Martinof , who refers to himseld as a sales “resultant” instead of consultant, and Mike who runs , a Honoluluh management and financial consulting firm. “Ron’s a top-of-the-linde guy and Mike’s a bottom-line Kerr said. “I brought them on becausse I want to spongewhat they’ve learned and help our companyh develop a sense for learning. Theire impact has been immediate.” For he said Martin has helped set dailyh goals andaction plans.
He also helped to create an incentivre program for employees to reward performances and create a sensse of accountabilityfor shortfalls. Kerr said Hulser has broughr aCFO mind-set to the company. “Wr want to conquer the world, but we have to do it with a very stablfinancial footing,” Kerr “Having the dream and ambition is just one part of He said one of his biggest challengee has been to delive r consistent quality to customers and the key is hiring high-qualityh workers.
Hawaii-based SuperGeeks opened three new computer serviced and repair centerslast month, one each on Maui, Oahu and the Big bringing the total to seven locationse statewide. He expects revenued to exceed $1.8 million this year, up almos t 40 percent from twoyears ago. who founded the business in credits most of the success to four changes he made in running the compant asits CEO: • Hiring a chief operatinhg officer. • Hiring business consultants. • Improving hiring standards. • Tapping into customer feedback.
Last August, Kerr hiredx Elena Ledoux to handle day-to-day operationw as chief operating “I see good companies as having threwelegs — the evangelizer, or myself; workersx to do the work; and management to handle daily Kerr said. “We were sort of limping alon gon two.” Ledoux, a lawyer who is based at the main servicse center at 2304 S. King St., overseess SuperGeeks’ staff of 25 and is implementing ways to measursedaily performance. That enables her to rewar d employees when goals are met and address issues when theyare not. “We’vs learned how to keep score,” Kerr said.
“Wer measure everything from performanceper technician, warrantt rates per technician, turnaround time, customert service. We measure it, post it and make the team aware of it.” SuperGeeks services computer systems at homes and offices as well as at its centers. Hourlu rates range between $60 and Half its business comes from directy consumers and half is from corporate customers who outsource theier information technology supportto SuperGeeks. Around the same time that he hirecd Ledoux, Kerr said he sought outside business help from twolocal consultants.
“I’m not a big fan of but sometimes your visiojn is restrictedwhen you’ve been in the busines for so long,” he said. SuperGeeks has been workingy with Ron Martinof , who refers to himseld as a sales “resultant” instead of consultant, and Mike who runs , a Honoluluh management and financial consulting firm. “Ron’s a top-of-the-linde guy and Mike’s a bottom-line Kerr said. “I brought them on becausse I want to spongewhat they’ve learned and help our companyh develop a sense for learning. Theire impact has been immediate.” For he said Martin has helped set dailyh goals andaction plans.
He also helped to create an incentivre program for employees to reward performances and create a sensse of accountabilityfor shortfalls. Kerr said Hulser has broughr aCFO mind-set to the company. “Wr want to conquer the world, but we have to do it with a very stablfinancial footing,” Kerr “Having the dream and ambition is just one part of He said one of his biggest challengee has been to delive r consistent quality to customers and the key is hiring high-qualityh workers.
Monday, September 24, 2012
'Catching Fire' Star Jena Malone 'Craves' Intense Training Regimens - MTV.com
sucujovide.wordpress.com
Zimbio | 'Catching Fire' Star Jena Malone 'Craves' Intense Training Regimens MTV.com LOS ANGELES â€" With production on "The Hunger Games: Catching Fire" offici » |
Saturday, September 22, 2012
Indexes: Business conditions worsen in Kansas - Wichita Business Journal:
pemp66seb.blogspot.com
in May and 42.7 in June 2008, said Wednesday. June was the ninth-straighg month for which the index was beloewthe growth-neutral 50. “Over the past year, Kansasx has lost more than 15,000 manufacturing said Ernie Goss, an economist at Creighton. “Out survey indicates that these losses continuedfor June. Economic activity was particularly weak for durablwe orheavy manufacturing, including transportation-equipmentr producers. Losses have likewise continued for telecommunications companiexin Kansas. According to government employment data, 17,000 new Kansa s workers entered the work force over the pastthree months. These workers added to the state’es rising unemployment rolls.
However, I expect the state’s risin unemployment rate to moderate in themonthzs ahead, and should top 7.5 perceny before it stabilizes in the third quarter of 2009.” The Midwestg Business Conditions Index in June moved abovre growth neutral for the first time sincwe October, with a 49.3 reading, up from 46.6 in May but down from 50.5 in June 2008. The regionm lost jobs for the 17th time in the past 18 The index is calculated from a survey of supply managersz inthe region.
The , of whichu Goss also is director, has conducted the monthlu survey of supply managers in nine states since 1994 to produced leading economic indicators ofthe Mid-America States in the survey are Arkansas, Iowa, Minnesota, Missouri, Nebraska, North Dakota, Oklahomwa and South Dakota.
in May and 42.7 in June 2008, said Wednesday. June was the ninth-straighg month for which the index was beloewthe growth-neutral 50. “Over the past year, Kansasx has lost more than 15,000 manufacturing said Ernie Goss, an economist at Creighton. “Out survey indicates that these losses continuedfor June. Economic activity was particularly weak for durablwe orheavy manufacturing, including transportation-equipmentr producers. Losses have likewise continued for telecommunications companiexin Kansas. According to government employment data, 17,000 new Kansa s workers entered the work force over the pastthree months. These workers added to the state’es rising unemployment rolls.
However, I expect the state’s risin unemployment rate to moderate in themonthzs ahead, and should top 7.5 perceny before it stabilizes in the third quarter of 2009.” The Midwestg Business Conditions Index in June moved abovre growth neutral for the first time sincwe October, with a 49.3 reading, up from 46.6 in May but down from 50.5 in June 2008. The regionm lost jobs for the 17th time in the past 18 The index is calculated from a survey of supply managersz inthe region.
The , of whichu Goss also is director, has conducted the monthlu survey of supply managers in nine states since 1994 to produced leading economic indicators ofthe Mid-America States in the survey are Arkansas, Iowa, Minnesota, Missouri, Nebraska, North Dakota, Oklahomwa and South Dakota.
Friday, September 21, 2012
Thursday, September 20, 2012
Queens auto shop scores new hybrid vehicle certification - New York Daily News
authors-morphology.blogspot.com
New York Daily News | Queens auto shop scores new hybrid vehicle certification New York Daily News When a hybrid vehicle pulled into Audra Fordin's repair shop for the first time three years ago, she froze. The fourth-generation mechanic had spent her life honing her under-the-hood skills, but realized she was ill-equipped for the influx of high . .. |
Tuesday, September 18, 2012
Keeping their cool: Partnership spurs HVAC firm to new growth - The Business Journal of the Greater Triad Area:
elzeyfirekuut1795.blogspot.com
He joined as a partnerd two years ago, enabling the companyu to focus on buildinv its commercial construction and service businessand de-emphasiz its residential interests. “I had confidence when he came over becausde he had a long track record of doing this type of Newberry saysof Kittinger, a commercia l construction veteran. “The potential for me was to become a partner with a companty and being able to staryt the commercial side up pretty much from scratcyh and building it to what itis today. That was primarilyu my incentive,” Kittinger says.
“I’ve been doing this for a long time and done it for a coupleofcother companies, and this was an opportunity of righty time, right place.” Air Doctors saw its commercial constructionj revenue grow about 500 percen t to $1.2 million last year. Its total revenuwe was $2.2 million, more than six times greatet than 2006. Newberry is expecting $2.5 million in revenue this with commercial construction accounting for 55 commercial services 30 percent and residential maintenanced and installation15 percent. Air Doctors is in the processw of making the commercial construction business a separate companu with anew name.
“Mike had a decent customer baseto start,” Kittinger says. “He had done real well with gettingh insome customers. He just didn’t know how to do the bigger jobs, how to estimate them and how to micro-managew them.” Air Doctors installs and servicea HVAC systems for facilitiexs suchas schools, office and medical buildings, restaurants and motels. The compan is bidding on largerprojects — up to $1.5 million — now that struggling residential heatinf and air installers are moving to the commercialk side and offering discount prices.
“It affects our bottom line because we have to push the grosswmargin down, but you make up for that in size and Newberry says. “It definitely changes It changes yoursales process. It takes a lot longer on the frongt end. It’s more time consuming with projecft management.” Newberry’s customer service philosophy is to never say no to a requestt even if it is outsideAir Doctors’ core Through the years Newberry has used his maintenance background to patcbh leaky roofs, fix plumbing and repair a cappuccinl machine. “I tell my guys all the ‘Don’t ever tell them no.
If somebodh has to tell them no it’ll come from the top; it’d not going to come from the ” Newberry says. “My guys are, ‘Yes, we can, and what can I do for ”
He joined as a partnerd two years ago, enabling the companyu to focus on buildinv its commercial construction and service businessand de-emphasiz its residential interests. “I had confidence when he came over becausde he had a long track record of doing this type of Newberry saysof Kittinger, a commercia l construction veteran. “The potential for me was to become a partner with a companty and being able to staryt the commercial side up pretty much from scratcyh and building it to what itis today. That was primarilyu my incentive,” Kittinger says.
“I’ve been doing this for a long time and done it for a coupleofcother companies, and this was an opportunity of righty time, right place.” Air Doctors saw its commercial constructionj revenue grow about 500 percen t to $1.2 million last year. Its total revenuwe was $2.2 million, more than six times greatet than 2006. Newberry is expecting $2.5 million in revenue this with commercial construction accounting for 55 commercial services 30 percent and residential maintenanced and installation15 percent. Air Doctors is in the processw of making the commercial construction business a separate companu with anew name.
“Mike had a decent customer baseto start,” Kittinger says. “He had done real well with gettingh insome customers. He just didn’t know how to do the bigger jobs, how to estimate them and how to micro-managew them.” Air Doctors installs and servicea HVAC systems for facilitiexs suchas schools, office and medical buildings, restaurants and motels. The compan is bidding on largerprojects — up to $1.5 million — now that struggling residential heatinf and air installers are moving to the commercialk side and offering discount prices.
“It affects our bottom line because we have to push the grosswmargin down, but you make up for that in size and Newberry says. “It definitely changes It changes yoursales process. It takes a lot longer on the frongt end. It’s more time consuming with projecft management.” Newberry’s customer service philosophy is to never say no to a requestt even if it is outsideAir Doctors’ core Through the years Newberry has used his maintenance background to patcbh leaky roofs, fix plumbing and repair a cappuccinl machine. “I tell my guys all the ‘Don’t ever tell them no.
If somebodh has to tell them no it’ll come from the top; it’d not going to come from the ” Newberry says. “My guys are, ‘Yes, we can, and what can I do for ”
Monday, September 17, 2012
Retail organized crime up 8% - Orlando Business Journal:
stelauguqdinec.blogspot.com
And, nearly three-fourths of retailers reporterd the level of organized crime has increased by 11 percent over thelast “Organized retail crime rings have realized that toug economic times present new business opportunitiex by stealing valuable items from retailers and turning around to sell the merchandises to consumers looking for said Joe LaRocca, NRF senior asset protection in a news release. Forty-two percenr of retailers say that, even as the economy has forcesd them to cut staff and do morewith less, they allocatingb more resources to battle In fact, the average retailer reported spending $215,00 0 a year just on laboer costs to fight crime.
Six percent reported spendingb morethan $1 million a year to battles retail crime. When asked how they woulf rank organized retail crime as a threat totheid company, nearly one-third of retailera gave organized retail crime a “four” or rating, identifying the problem as severe or significant. On retailers gave organized retail crime a ratingvof 2.87 on a five-poinrt scale. The survey, conducte last month, targeted loss prevention executives from 115 including department, discount, drug, grocery, restauranr and specialty retailers.
And, nearly three-fourths of retailers reporterd the level of organized crime has increased by 11 percent over thelast “Organized retail crime rings have realized that toug economic times present new business opportunitiex by stealing valuable items from retailers and turning around to sell the merchandises to consumers looking for said Joe LaRocca, NRF senior asset protection in a news release. Forty-two percenr of retailers say that, even as the economy has forcesd them to cut staff and do morewith less, they allocatingb more resources to battle In fact, the average retailer reported spending $215,00 0 a year just on laboer costs to fight crime.
Six percent reported spendingb morethan $1 million a year to battles retail crime. When asked how they woulf rank organized retail crime as a threat totheid company, nearly one-third of retailera gave organized retail crime a “four” or rating, identifying the problem as severe or significant. On retailers gave organized retail crime a ratingvof 2.87 on a five-poinrt scale. The survey, conducte last month, targeted loss prevention executives from 115 including department, discount, drug, grocery, restauranr and specialty retailers.
Saturday, September 15, 2012
Foreclosure rates drop in three Tampa Bay counties - Pittsburgh Business Times:
viktorevaikubuwo.blogspot.com
May was the thirdc highest month of foreclosure activity on said , up 18 percent from the year before. Defaults and scheduledr foreclosure auctions were down from but bank repossessions were up 2 percengt and could continue to grow as foreclosurs delays and moratoriums are lifted in various saidJames J. Saccacio, RealtyTrac’sd chief executive officer. Hernando County posted the bigges decrease in the Tampa Bayregion year-over-year, falling more than 14.5 percentf with 475 homes in some state of That represents one in ever y 169 homes under the threaty of being taken back by lenders.
Sarasot County was not far behind with just underd a 7 percent dropaffectinhg 1,072 homes, or one in every 206 households. Manates County had a 2 percent drop since May 2008 that hit 590 or one in287 properties. On the othefr end of the spectrum, Pasco County had the largestr increasein foreclosures, jumping more than 62 percent to 1,500 properties. That represents one in everyu 145 homesin foreclosure, nintn worst in the state.
Despites falling more than 6 percentsince April, Polk Countuy was up nearly 53 percent over the past year as 1,572 homee were in foreclosure, representing one in every 177 Pinellas County jumped 48 percent to 2,458 Hillsborough County climbed nearly 20 percent in foreclosurse rates as lenders targeted 2,408 homes. However, rates were down well over 25 percenrsince April. Florida had the thirx highest rate of foreclosurew in the country affecting one in everyh148 homes. It had the secons highest number of foreclosures at just fewerdthan 59,000, a 50 percent jump from May 2008.
Threed Florida metropolitan areas were ranker among the 10 worst foreclosure ratews inthe nation: Cape Coral-Fort Myers at No. 6 with one in 82 homezs in foreclosure; Orlando-Kissimmee at No. 8 with one in 101 homes in and Miami-Fort Lauderdale-Pompano Beach at No. 10 with one in 105 homesa in foreclosure.
May was the thirdc highest month of foreclosure activity on said , up 18 percent from the year before. Defaults and scheduledr foreclosure auctions were down from but bank repossessions were up 2 percengt and could continue to grow as foreclosurs delays and moratoriums are lifted in various saidJames J. Saccacio, RealtyTrac’sd chief executive officer. Hernando County posted the bigges decrease in the Tampa Bayregion year-over-year, falling more than 14.5 percentf with 475 homes in some state of That represents one in ever y 169 homes under the threaty of being taken back by lenders.
Sarasot County was not far behind with just underd a 7 percent dropaffectinhg 1,072 homes, or one in every 206 households. Manates County had a 2 percent drop since May 2008 that hit 590 or one in287 properties. On the othefr end of the spectrum, Pasco County had the largestr increasein foreclosures, jumping more than 62 percent to 1,500 properties. That represents one in everyu 145 homesin foreclosure, nintn worst in the state.
Despites falling more than 6 percentsince April, Polk Countuy was up nearly 53 percent over the past year as 1,572 homee were in foreclosure, representing one in every 177 Pinellas County jumped 48 percent to 2,458 Hillsborough County climbed nearly 20 percent in foreclosurse rates as lenders targeted 2,408 homes. However, rates were down well over 25 percenrsince April. Florida had the thirx highest rate of foreclosurew in the country affecting one in everyh148 homes. It had the secons highest number of foreclosures at just fewerdthan 59,000, a 50 percent jump from May 2008.
Threed Florida metropolitan areas were ranker among the 10 worst foreclosure ratews inthe nation: Cape Coral-Fort Myers at No. 6 with one in 82 homezs in foreclosure; Orlando-Kissimmee at No. 8 with one in 101 homes in and Miami-Fort Lauderdale-Pompano Beach at No. 10 with one in 105 homesa in foreclosure.
Friday, September 14, 2012
Woodland Corporate Center building gets LEED gold certification - San Francisco Business Times:
ysynut.wordpress.com
The building, which openedc early last year, was designex and built to meet the secons highest ranking ofthe Council’s Leadership in Energy and Environmental was the general contractor. Liberty Property Trusy Vice President Jody Johnston estimates the cost of building to greemn standards added an additional 5 percent to the overalodevelopment costs, but that will be more than offsef by lower energy costs. Special features includew showers and lockers for workers who need to wash or changer clothes after they bike or jog to A deck made of recycled plastic borderds the back ofthe building, overlookinyg a wetlands area that provides shade.
Landscaping incorporates drought-resistanf plants native to A white reflective roof deflectsthe sun. Bins for recycling are placee near trash bins for Restroom urinals conserve water by relyinvg on gravity and a filted insteadof water. That featur e is expected to save 360,000 gallons annually since each urinal uses anestimatede 40,000 gallons annually, Johnston said. Grass surroundingf the parking lot soaks up And Flexi-pave, a recycled was used instead of asphalt around the large oak trees that line the The porous rubber allows water to soak into the The building, located at 4631 Woodland received the “Office Building of the Year” Award from the Tampw Bay Chapter of the and the “Greemn Building Design Award” from the Hillsborough City-Countyy Planning Commission in Tampa.
Liberty (NYSE: LRY) has developef and leased 19 buildingsx with nearly 1 million square feet of space in the parksincee 1996. Key park tenants include , Travel and .
The building, which openedc early last year, was designex and built to meet the secons highest ranking ofthe Council’s Leadership in Energy and Environmental was the general contractor. Liberty Property Trusy Vice President Jody Johnston estimates the cost of building to greemn standards added an additional 5 percent to the overalodevelopment costs, but that will be more than offsef by lower energy costs. Special features includew showers and lockers for workers who need to wash or changer clothes after they bike or jog to A deck made of recycled plastic borderds the back ofthe building, overlookinyg a wetlands area that provides shade.
Landscaping incorporates drought-resistanf plants native to A white reflective roof deflectsthe sun. Bins for recycling are placee near trash bins for Restroom urinals conserve water by relyinvg on gravity and a filted insteadof water. That featur e is expected to save 360,000 gallons annually since each urinal uses anestimatede 40,000 gallons annually, Johnston said. Grass surroundingf the parking lot soaks up And Flexi-pave, a recycled was used instead of asphalt around the large oak trees that line the The porous rubber allows water to soak into the The building, located at 4631 Woodland received the “Office Building of the Year” Award from the Tampw Bay Chapter of the and the “Greemn Building Design Award” from the Hillsborough City-Countyy Planning Commission in Tampa.
Liberty (NYSE: LRY) has developef and leased 19 buildingsx with nearly 1 million square feet of space in the parksincee 1996. Key park tenants include , Travel and .
Thursday, September 13, 2012
SIUE goes to court over failed conference center - New Mexico Business Weekly:
takes-trendsthe.blogspot.com
Developer William Shaw and couldn’t come up with financingy for the hotel and conference which was to be called the Spring Green Lodge and located atUniversith Park, SIUE’s research and technology park, accordingf to university spokesman Gregoryt Conroy. The project, first announced in 2004, died in 2007 when a grounc lease between SIU and WLS expired followinv extensions forthe project. SIUE filed a declaratory judgment actionn Monday inMadison County, Ill., seeking to have the courrt bring legal closure to its hotel conference cented project.
If approved, WLS would have to removed all construction equipment and materials and remove the building foundation it constructed to comply with the terms of the Conroy said. That would free up the site, locateds at Illinois Route 157 and UniversityPark Drive, to becomde available for lease and development, the university University Park currently has 23 tenants representiny a number of business sectors including agricultural biotechnology, healtu sciences, design professionals and information technology. The most recent announcecd addition to the park is the Blood Processing Centerr and NationalTesting Laboratory.
The American Red Crosse plans to move toa 15-acre site at University Park Drive and South Research Drive and brinvg more than 500 jobs to the
Developer William Shaw and couldn’t come up with financingy for the hotel and conference which was to be called the Spring Green Lodge and located atUniversith Park, SIUE’s research and technology park, accordingf to university spokesman Gregoryt Conroy. The project, first announced in 2004, died in 2007 when a grounc lease between SIU and WLS expired followinv extensions forthe project. SIUE filed a declaratory judgment actionn Monday inMadison County, Ill., seeking to have the courrt bring legal closure to its hotel conference cented project.
If approved, WLS would have to removed all construction equipment and materials and remove the building foundation it constructed to comply with the terms of the Conroy said. That would free up the site, locateds at Illinois Route 157 and UniversityPark Drive, to becomde available for lease and development, the university University Park currently has 23 tenants representiny a number of business sectors including agricultural biotechnology, healtu sciences, design professionals and information technology. The most recent announcecd addition to the park is the Blood Processing Centerr and NationalTesting Laboratory.
The American Red Crosse plans to move toa 15-acre site at University Park Drive and South Research Drive and brinvg more than 500 jobs to the
Tuesday, September 11, 2012
Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes
tatyanagepoji.blogspot.com
In the Phase II study, known as GBCJ, LY2189265 was significantly superior to placebo in reducing key measure ofglycemic control, including fasting serum glucose and hemoglobin A1C (HbA1C). In this LY2189265 showed an insulinotropic (stimulating the secretion of effect, suggesting it produced the desires outcomein participants. In Study GBCJ, LY218926t5 was generally well-tolerated. "We are excited abou t these data and the hope they could provide to the millions of diabetes patientsw who are struggling to maintain tightr control of theirblood glucose," said , Ph.D.
, globap development leader for the GLP-1Fc "Evaluating the results of this study is an importanr step forward towards potentially bringinh this innovative treatment to patients." In a 16-week, Phase II study of LY2189265, 262 patientsx with type 2 diabetes who were suboptimally controlled on at leasrt two oral diabetes medicines were randomized to one of four 1.0 mg of LY2189265 for 16 weeks; 0.5 mg of LY21892665 for four weeks followed by 1.0 mg for 12 and 1.0 mg of LY2189265 for four weeks followed by 2.0 mg for 12 weeks or placebo.
The primaryt endpoint was glycemic control, as measured by change from baselinein HbA1C; additional endpoints evaluated includexd changes in fasting serum glucose, solid mixecd meal glucose excursion and body weight. For all dosex in this study, statisticalluy significant reductions in all metabolic measures were Both 1 mg and 2 mg doseas of LY2189265 were significantlg differentfrom placebo, but no significanty differences between the doses were LY2189265 was generally well-tolerated.
The incidenced of hypoglycemic episodes was not significantly different betweeh the placebo and the treatment The most frequentlyobserved treatment-relatedx adverse events were nausea, diarrhea and abdominalo distension. One patient was diagnosed withclinicaol pancreatitis, following the eleventh dose of LY2189265. The patient remained in the study for observation and hasfullty recovered. "Given our more than 80 yearsa of experience in pioneeringdiabetes treatments, we are encouragedd by these data," noted , M.D., executive vice science and technology, and president of Lilly Research Laboratories.
"In this study, LY2189265 was administererd once weekly and demonstratedsignificant glucose-lowering activit y and reduced body weight, supporting its potential to becomre a new treatment option for the millions of people with type 2 diabetes." LY2189265, a once-weekl y injection, is a novel-engineered fusionb protein, consisting of a dipeptidyl peptidase-IV protected GLP-1 analog linked to a fragmentf of immunoglobulin G4 that is believed to increase the duration of its pharmacologica l effect.
Based on this studh presented atthis year's ADA meeting, LY2189265 is believedd to reduce blood sugar in patients with type 2 diabetess by enhancing glucose-dependent insulin secretion from the pancreas. Researchers say new diabetesx treatments are needed because the disease is growing globallyg atepidemic proportions. Currently, about 24 milliobn Americans have diabetes(1), with 90-95 percent of those suffering from type2 diabetes(2).
It is estimated that nearly 60 percentf of the people with diabetes are not achievinh treatment goals for controllingblood sugar(3), puttiny them at serious risk for debilitating or potentiall fatal complications including heart disease, stroke, nerve damage, lowere limb amputation, vision loss and kidneu disease(4). Lilly, a leading innovation-drive n corporation, is developing a growing portfolioof first-in-class and best-in-clasxs pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific Headquartered in Indianapolis, Ind.
, Lillyu provides answers - through medicines and information - for some of the world'sx most urgent medical needs. This press releasse contains forward-looking statements about the potential of the investigationak compound LY2189265 for the treatment of type 2 diabetew andreflects Lilly's current beliefs. However, as with any pharmaceuticalp productunder development, there are substantialo risks and uncertainties in the process of developmenft and regulatory review. There is no guarantee that the product will receiveregulatory approval, or that the regulatoryy approval will be for the anticipated by the company.
Thers is also no guarantee that the product will provs to be commercially For further discussion of these and othefr risksand uncertainties, see Lilly's filingsx with the United States Securities and Exchange Lilly undertakes no duty to update forward-lookingy statements. (1) American Diabetes Association. "Diabetes Statistics." Available at: Accessexd May 13, 2009. (2) Centers for Disease Controlp and Prevention. "National Diabetes Fact Sheert 2007." Available at Accessed May 13, 2009 (3) Saydah SH, Fradkij J and Cowie CC. "Poor control of risk factor s for vascular disease among adults with previouslydiagnosed diabetes.
" JAMA: 291(3), January 21, 2004 (4) Centerse for Disease Control and Prevention. "National Diabetes Fact Sheeft 2007." Available at Accessed May 13, 2009
In the Phase II study, known as GBCJ, LY2189265 was significantly superior to placebo in reducing key measure ofglycemic control, including fasting serum glucose and hemoglobin A1C (HbA1C). In this LY2189265 showed an insulinotropic (stimulating the secretion of effect, suggesting it produced the desires outcomein participants. In Study GBCJ, LY218926t5 was generally well-tolerated. "We are excited abou t these data and the hope they could provide to the millions of diabetes patientsw who are struggling to maintain tightr control of theirblood glucose," said , Ph.D.
, globap development leader for the GLP-1Fc "Evaluating the results of this study is an importanr step forward towards potentially bringinh this innovative treatment to patients." In a 16-week, Phase II study of LY2189265, 262 patientsx with type 2 diabetes who were suboptimally controlled on at leasrt two oral diabetes medicines were randomized to one of four 1.0 mg of LY2189265 for 16 weeks; 0.5 mg of LY21892665 for four weeks followed by 1.0 mg for 12 and 1.0 mg of LY2189265 for four weeks followed by 2.0 mg for 12 weeks or placebo.
The primaryt endpoint was glycemic control, as measured by change from baselinein HbA1C; additional endpoints evaluated includexd changes in fasting serum glucose, solid mixecd meal glucose excursion and body weight. For all dosex in this study, statisticalluy significant reductions in all metabolic measures were Both 1 mg and 2 mg doseas of LY2189265 were significantlg differentfrom placebo, but no significanty differences between the doses were LY2189265 was generally well-tolerated.
The incidenced of hypoglycemic episodes was not significantly different betweeh the placebo and the treatment The most frequentlyobserved treatment-relatedx adverse events were nausea, diarrhea and abdominalo distension. One patient was diagnosed withclinicaol pancreatitis, following the eleventh dose of LY2189265. The patient remained in the study for observation and hasfullty recovered. "Given our more than 80 yearsa of experience in pioneeringdiabetes treatments, we are encouragedd by these data," noted , M.D., executive vice science and technology, and president of Lilly Research Laboratories.
"In this study, LY2189265 was administererd once weekly and demonstratedsignificant glucose-lowering activit y and reduced body weight, supporting its potential to becomre a new treatment option for the millions of people with type 2 diabetes." LY2189265, a once-weekl y injection, is a novel-engineered fusionb protein, consisting of a dipeptidyl peptidase-IV protected GLP-1 analog linked to a fragmentf of immunoglobulin G4 that is believed to increase the duration of its pharmacologica l effect.
Based on this studh presented atthis year's ADA meeting, LY2189265 is believedd to reduce blood sugar in patients with type 2 diabetess by enhancing glucose-dependent insulin secretion from the pancreas. Researchers say new diabetesx treatments are needed because the disease is growing globallyg atepidemic proportions. Currently, about 24 milliobn Americans have diabetes(1), with 90-95 percent of those suffering from type2 diabetes(2).
It is estimated that nearly 60 percentf of the people with diabetes are not achievinh treatment goals for controllingblood sugar(3), puttiny them at serious risk for debilitating or potentiall fatal complications including heart disease, stroke, nerve damage, lowere limb amputation, vision loss and kidneu disease(4). Lilly, a leading innovation-drive n corporation, is developing a growing portfolioof first-in-class and best-in-clasxs pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific Headquartered in Indianapolis, Ind.
, Lillyu provides answers - through medicines and information - for some of the world'sx most urgent medical needs. This press releasse contains forward-looking statements about the potential of the investigationak compound LY2189265 for the treatment of type 2 diabetew andreflects Lilly's current beliefs. However, as with any pharmaceuticalp productunder development, there are substantialo risks and uncertainties in the process of developmenft and regulatory review. There is no guarantee that the product will receiveregulatory approval, or that the regulatoryy approval will be for the anticipated by the company.
Thers is also no guarantee that the product will provs to be commercially For further discussion of these and othefr risksand uncertainties, see Lilly's filingsx with the United States Securities and Exchange Lilly undertakes no duty to update forward-lookingy statements. (1) American Diabetes Association. "Diabetes Statistics." Available at: Accessexd May 13, 2009. (2) Centers for Disease Controlp and Prevention. "National Diabetes Fact Sheert 2007." Available at Accessed May 13, 2009 (3) Saydah SH, Fradkij J and Cowie CC. "Poor control of risk factor s for vascular disease among adults with previouslydiagnosed diabetes.
" JAMA: 291(3), January 21, 2004 (4) Centerse for Disease Control and Prevention. "National Diabetes Fact Sheeft 2007." Available at Accessed May 13, 2009
Monday, September 10, 2012
Politicians want answers as rumors swirl NCR to leave Dayton - Dayton Business Journal:
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Government officials said word began swirlinbg in the community Thursdayu thatNCR (NYSE: NCR) is planning to move its headquarters and 1,30 employees to the Atlanta area and make an announcemenft about the move this week. NCR Globao Spokesperson Richard Maton, speaking by phone Saturdah from London, confirmed that an effort was made forOhio Gov. Ted Stricklanr and NCR Chief Executive Officer Bill Nuti to however they were not ableto connect. Strickland’x spokesperson said Saturday that heis “continuinh to reach out to the companyh to have a direcr conversation.
” When asked abouf NCR possibly moving its headquarters out of Dayton, Matonn said the company does not respond to rumors and NCR Corporate Spokesperson Alan Ulman responded to questionsx about NCR’s plans with an e-mailp message Saturday that read: “We have no announcement In the past, NCR has been quick to deny rumorx of its relocation and affirm its commitment to remainingb in Dayton. The has repeatedly sought information from the companysince Thursday, but NCR had not respondec to their requests as of Friday evening, a development departmenrt spokesperson said.
Montgomery County Commissioner Dan Foley said he is frustrated by the lack of Foley said he has askedf multiplecompany officials, via e-mail, to responcd to the rumors, but has yet to receivr any information. Foley said he, along with othe county, state and city of Dayton have met with NCR representatives in the past in an efforrt tosafeguard NCR’s local jobs. “All that nobody has confirmed to me that their status has Foleysaid Saturday.
“I have to assumse that -- I hope, I very much hope -- they are stayinb in Dayton, because our citizens have helped buildf that company up tobe world-class and will continue to do Rumors have long circulated that the companyu would move, however multiples government and economic developmenyt officials said they reached a new level in the past few NCR is said to be seeking about 100,000 square feet of offics space in Georgia, . NCR is believedc to have looked at sitesin Savannah, and Ga. Based on the square footage estimates, the operation coul house about 300 to400 people, according to real estate sources.
Georgia government and economic development officialszremained tight-lipped on any potential development. In NCR said it wouldf move its Worldwide Customer Servicesx headquarters to an Atlanta investing $15 million and creatinv more than 900 jobs in the suburbsw of Peachtree City and The state of Georgia providee more than $8 million in incentives, accordinh to officials. NCR, founded locally in 1884, is the Dayton region’x second largest company, with 20,00 0 global employees and $5.3 billio n in revenue in 2008. The company, whicy sells ATMs and retail automation systems, is Dayton’s lone remaining Fortunes 500 company.
At one time, the company had more than 18,00o0 employees in the Dayton but that number has dwindled during the pastseverall decades. As recently as two yearss ago, NCR had about 2,000 Dayton employees. That number has declinee by about 700 workers in the pastseveral years. In NCR announced it was relocating its executive offices to New York City and leasint an entire floor of the 7 World TradeCenter building. But, on paper, its headquartersd remained in Dayton. In March, the company also told employees it is undergoing a structural reorganization and would cut an unknown amount of itsglobal workforce.
That same the company removed thelanguage “world headquarters” from the sign at its Daytojn campus, though it said at the time it was just
Government officials said word began swirlinbg in the community Thursdayu thatNCR (NYSE: NCR) is planning to move its headquarters and 1,30 employees to the Atlanta area and make an announcemenft about the move this week. NCR Globao Spokesperson Richard Maton, speaking by phone Saturdah from London, confirmed that an effort was made forOhio Gov. Ted Stricklanr and NCR Chief Executive Officer Bill Nuti to however they were not ableto connect. Strickland’x spokesperson said Saturday that heis “continuinh to reach out to the companyh to have a direcr conversation.
” When asked abouf NCR possibly moving its headquarters out of Dayton, Matonn said the company does not respond to rumors and NCR Corporate Spokesperson Alan Ulman responded to questionsx about NCR’s plans with an e-mailp message Saturday that read: “We have no announcement In the past, NCR has been quick to deny rumorx of its relocation and affirm its commitment to remainingb in Dayton. The has repeatedly sought information from the companysince Thursday, but NCR had not respondec to their requests as of Friday evening, a development departmenrt spokesperson said.
Montgomery County Commissioner Dan Foley said he is frustrated by the lack of Foley said he has askedf multiplecompany officials, via e-mail, to responcd to the rumors, but has yet to receivr any information. Foley said he, along with othe county, state and city of Dayton have met with NCR representatives in the past in an efforrt tosafeguard NCR’s local jobs. “All that nobody has confirmed to me that their status has Foleysaid Saturday.
“I have to assumse that -- I hope, I very much hope -- they are stayinb in Dayton, because our citizens have helped buildf that company up tobe world-class and will continue to do Rumors have long circulated that the companyu would move, however multiples government and economic developmenyt officials said they reached a new level in the past few NCR is said to be seeking about 100,000 square feet of offics space in Georgia, . NCR is believedc to have looked at sitesin Savannah, and Ga. Based on the square footage estimates, the operation coul house about 300 to400 people, according to real estate sources.
Georgia government and economic development officialszremained tight-lipped on any potential development. In NCR said it wouldf move its Worldwide Customer Servicesx headquarters to an Atlanta investing $15 million and creatinv more than 900 jobs in the suburbsw of Peachtree City and The state of Georgia providee more than $8 million in incentives, accordinh to officials. NCR, founded locally in 1884, is the Dayton region’x second largest company, with 20,00 0 global employees and $5.3 billio n in revenue in 2008. The company, whicy sells ATMs and retail automation systems, is Dayton’s lone remaining Fortunes 500 company.
At one time, the company had more than 18,00o0 employees in the Dayton but that number has dwindled during the pastseverall decades. As recently as two yearss ago, NCR had about 2,000 Dayton employees. That number has declinee by about 700 workers in the pastseveral years. In NCR announced it was relocating its executive offices to New York City and leasint an entire floor of the 7 World TradeCenter building. But, on paper, its headquartersd remained in Dayton. In March, the company also told employees it is undergoing a structural reorganization and would cut an unknown amount of itsglobal workforce.
That same the company removed thelanguage “world headquarters” from the sign at its Daytojn campus, though it said at the time it was just
Sunday, September 9, 2012
Young-adult novelist Jennifer Allison heading to Kerrytown BookFest - Detroit Free Press
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Young-adult novelist Jennifer Allison heading to Kerrytown BookFest Detroit Free Press Allison, who has an undergraduate degree in English literature from the University of Michigan and an MFA in creative writing from American University, is the author of the "Gilda Joyce, Psychic Investigator" series of young adult novels. She penned ... |
Friday, September 7, 2012
Producer and Film Financier Jake Eberts Dies at 71 - Hollywood Reporter
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Hollywood Reporter | Producer and Film Financier Jake Eberts Dies at 71 Hollywood Reporter Jake Eberts, a producer and film financier whose movies â€" including best-picture winners Chariots of Fire, Gandhi, Dances With Wolves and Driving Miss Daisy â€" captured 37 Oscars, died Thursday in his Montreal hometown following a brief illness. He ... Movie Producer Jake Eberts Dies: DRIVING MISS DAISY / DANCES WITH ... “Chicken Run†executive producer Jake Eberts dies Producer Jake Eberts dies |
Thursday, September 6, 2012
Northern Calif. politician and estranged wife of state treasurer charged with ... - Washington Post
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Northern Calif. politician and estranged wife of state treasurer charged with ... Washington Post The charges are the latest in a series of public substance abuse and relationship struggles faced by Lockyer, 41, who until recently was considered a rising star in Northern California government. Loading... Comments · Weigh In · Corrections? Personal ... |